Sabinyl acetate toxicity. 1%) and trans-sabinyl acetate (Table 5, ID 14) (11.

Sabinyl acetate toxicity. Toxic activity of these oils (G-J) ranged from 10. 0]hexan-3-ol, 4-methylene-1- (1-methylethyl)-, acetate Bicyclo [3. Who Should Avoid Ethylene vinyl acetate is a type of plastic — a polymer with a wide variety of uses, both residential and industrial. N auplii lethality (LC 50) ranged 15. myristicin Jan 1, 1996 · The steam volatile components from the hexane extract of dried flower buds of Egletes viscosa were identified by gas chromatography-mass spectrometry as trans -carvyl acetate, cis -carvyl acetate, sabinyl acetate, verbenyl acetate, cyclopentaethylidene, geranyl acetate and 5-methylfuranone, and trans -pinocarvyl acetate (major component). absinthium oils were found to be those containing appreciable amount of trans-sabinyl acetate (45. Sabinyl acetate | C12H18O2 | CID 94266 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Articles of Sabinyl acetate are included as well. 3%), while other samples with equivalent Sabinyl acetate is a naturally occurring bicyclic monoterpenoid. ↑ G. PubMed: Chemical characterization by GC-MS and in vitro activity against Candida albicans of volatile fractions prepared from Artemisia dracunculus, Artemisia abrotanum, Artemisia absinthium and Artemisia vulgaris. 2, KHY = 0. ca It is the acetate ester of sabinol and is characterized by a thujane (B1196268) skeleton, which consists of a fused cyclopropane (B1198618) and cyclopentane (B165970) ring system. It has a fragrant Rosin taste and is often used as an ingredient in spices or essences. e. 0]hexan-3-ol 3-acetate,Sabinyl acetate; find -PHL89271 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich Mar 11, 2024 · (1) Esperone is celestolide? (2) Sabinyl acetate would seem to unambiguously indicate presence of Juniperus sabina ("Savin") essential oil? Sabinyl acetate phyproof® Reference Substance; CAS Number: 53833-85-5; Synonyms: cis-Sabinyl acetate, (1S,3R,5S)-1-Isopropyl-4-methylenebicyclo [3. 0]hexan-3-ol, 4-methylene-1- (1-methylethyl)-, 3-acetate acetic acid (1 Toxicity of the products of Biodegradation: The products itself and its products of degradation are not toxic. The major concerns include causing abortion, reproductive hormone modulation, maternal toxicity, teratogenicity, and embryo-fetotoxicity. net This structure classifies it as a bicyclic monoterpenoid. 8 %), while during fruiting amount of this constituent made up 52. Content of toxic thujones was the highest during flowering, this fact is very important in wormwood gathering, because the plant is widely use in phytotherapy and as a 6 days ago · Material Safety Data Sheet or SDS for Tocopheryl acetate 7695-91-2 from chemicalbook for download or viewing in the browser Spanish sage (Salvia lavanda4folia Vahi. This work summarizes the important studies on the reproductive effects of essential oil constituents anethole, apiole, citral, camphor, thymoquinone, trans-sabinyl acetate, methyl salicylate, thujone This work summarizes the important studies on the reproductive effects of essential oil constituents anethole, apiole, citral, camphor, thymoquinone, trans-sabinyl acetate, methyl salicylate, thujone, pulegone, -elemene, -eudesmol, and costus lactone, among others. Apr 4, 2024 · Trans-Sabinyl acetate Generally recognized as safe, but high concentrations may cause skin irritation or sensitization It's important to use essential oils sparingly, dilute them, consult your healthcare practitioner or an aromatherapist, and/or do your own research before using products containing these chemical components. Information on this page: Gas Chromatography References Jan 1, 2016 · The maximum levels of the natural toxin thujone in foodstuffs and beverages are 0. 0]hexan-3-ol, 4-methylene-1- (1-methylethyl)-, acetate cis-Sabinyl acetate trans-Sabinyl acetate Permanent link for this species. 0]hexan-3-ol, 4-methylene-1- (1-methylethyl)-, acetate trans-Sabinyl acetate trans-Sabinyl acetate Other names: (Z)-Sabinyl acetate Permanent link for this species. The essential oil of Juniperus sabina, containing 50% sabinyl acetate, was administered s. From the non-volatile residue, centipedic acid and a SABINYL ACETATE SABINENE WITH GC 4 (10)-Thujen-3-ol, acetate 1-Isopropyl-4-methylenebicyclo [3. fragrans essential oil (EO) in higher yield and with a lower content of toxic phenylpropenoids (e. Aug 10, 2016 · Trans- sabinyl acetate was the only component that found in common and only in samples W3 and W4. The result indicates that the abortifacient effect of Juniperus sabina essential oil is related to an implantation inhibiting effect, induced by sabinyl acetate, the mechanism of which is being investigated. . The other samples (K-O) were characterized by the following first major constituents: 1,8-cineole, camphor, trans-thujone and cis-chrysanthenyl acetate. ca Dec 5, 2010 · Stereoisomers: (1S,3S,5S)-1-Isopropyl-4-methylenebicyclo [3. to mice at doses of 15, 45 and 135 mg/kg either on days 0–4 of pregnancy (implantation period May 1, 2020 · In both stems and leaves oils, trans-sabinyl acetate is found to be the major component demonstrating a presence of 24 and 20% in the studied oils, respectively. 1. 5. Plectranthus oil (60% sabinyl acetate) is embryotoxic, fetotoxic, teratogenic, and abortifacient [112]. Aug 12, 2025 · Substance summary NOSVHC (Substance of Very High Concern) NOPBT (Persistence, Bioaccumulation, Toxicity) NOvPvB (Very Persistent, Very Bioaccumulative) NOEndocrine Perturbator NOCMR (Carcinogenic, Mutagenic, Reprotoxic) NORespiratory sensitising properties NOEquivalent level of concern having probable serious effects to human health NOEquivalent level of concern having probable serious effects Mar 12, 2013 · Content of trans -sabinyl acetate significantly has changed, it was minor at leaves stage (0. Stereoisomers: (1S,3S,5S)-1-Isopropyl-4-methylenebicyclo [3. Feb 27, 2021 · This work summarizes the important studies on the reproductive effects of essential oil constituents anethole, apiole, citral, camphor, thymoquinone, trans-sabinyl acetate, methyl salicylate May 7, 2021 · cis-Sabinyl acetate | C12H18O2 | CID 6428460 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. May 1, 2022 · Natural deep eutectic solvents (NADES) have emerged as green extracting solvents in recent years. 7-31. ) is a wild or cultivated species of Labiatae, widely spread over the Mediterranean basin regions, mainly Sabinyl Acetate has antioxidant activity, it also shows antiimplantation effect on the abortifacient effect of Juniperus sabina essential oil. The oils could be attributed to two different chemotypes: sa binyl acetate + thujones and sabinyl acetate + (Z)-epoxy-oc imene. Achillea falcata essential oil characterization (aerial parts and roots) was performed near the city of Ma’loula, Syria, revealing the presence of two principal constituents, trans-sabinol (19. In: Planta Medica. Aug 3, 2021 · Its botanical name is Artemisia Absinthium or Artemisia Annua. Sabinyl acetate phyproof® Reference Substance; CAS Number: 53833-85-5; Synonyms: cis-Sabinyl acetate, (1S,3R,5S)-1-Isopropyl-4-methylenebicyclo [3. Sabinyl acetate - Introduction SABINYL ACETATE is an organic compound, which is one of the main components of Pinus camphor oil. pine camphoryl acetate is mainly used in cosmetics and personal care products such as perfume, soap, shower gel, shampoo, etc. 0]hexanyl) ethanoate Bicyclo [3. Mar 10, 2015 · Two oxygenated monoterpenes esters from A. 4 days ago · Acetate C9 Nonylic has a fruity and tropical note with aromatic undertones. 7+)(Fig. The most toxic A. Sabinyl acetate. Visit ChemicalBook To find more SABINYL ACETATE (3536-54-7) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. Synonyms: <I>cis</I>-Sabinyl acetate, (1<I>S</I>,3<I>R</I>,5<I>S</I>)-1-Isopropyl-4-methylenebicyclo [3. ) test. Development. 0]hex-3-yl acetate, (1<I>S</I>,3<I>R</I>,5 ChemicalBook 致力于为化学行业用户提供SABINYL ACETATE的性质、化学式、分子式、比重、密度,同时也包括SABINYL ACETATE的沸点、熔点、MSDS、用途、作用、毒性、价格、生产厂家、用途、上游原料、下游产品等信息。 ChemSpider record containing structure, synonyms, properties, vendors and database links for cis-Sabinyl acetate, 53833-85-5, PBWRFXQNNGSAQG-UTUOFQBUSA-N Jan 1, 2012 · The most toxic A. Functional use (s) - natural substances and extractivesArticles: PubMed: Chemical characterization by GC-MS and in vitro activity against Candida albicans of volatile fractions prepared from Artemisia dracunculus, Artemisia abrotanum, Artemisia absinthium and Artemisia vulgaris. (Z)-Sabinyl acetate | C12H18O2 | CID 171035627 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. to mice at doses of 15, 45 and 135 mg/kg either on days 0–4 of pregnancy (implantation period Functional use (s) - natural substances and extractivesUS / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: It acts through inhibiting implantation of the embryo [111]. The most toxic oils, G and H, were rich in germacrene D and davanones. Previous studies documented that A. Contribution to the Study ofSalvia lavandulifoliaEssential Oil: Potential Toxicity Attributable to Sabinyl Acetate Mar 12, 2013 · Content of trans -sabinyl acetate significantly has changed, it was minor at leaves stage (0. 6 % of total oil. absinthiumoils were found to be those containing appreciable amount of trans-sabinyl acetate (45. 0]hexan-3-ol 3-acetate,Sabinyl acetate at Sigma-Aldrich Research. Table 2. 05). ) is a wild or cultivated species of Labiatae, widely spread over the Mediterranean basin regions, mainly in Spain, and the presence of sabinyl acetate among the constituents of the essential oil is noteworthy. Thisalsosuggestedthat5 The most toxic A. 0]hexan-3-yl acetate cis-Sabinyl acetate trans Abreviaturas e siglas ADR: Agreement on Dangerous Goods by Road RID: Regulations concerning the International Transport of Dangerous Goods by Rail IATA: International Air Transport Association CAS: Chemical Abstract Service PBT: Persistent, Bioaccumulative and Toxic vPvB: Very Persistent and Very Bioaccumulative /CEE - Texto int In France, there are different chemotypes with trans-sabinyl-acetate and chrysanthenyl-acetate as main components, while plants from Eastern Europe are mostly mixed types (Chialva et al. The Food and Drug Administration (FDA) has stated that ethylene vinyl acetate is safe when used in food production, packaging or transportation, and it's not an especially dangerous material. In sample W1, β- thujone was the only compound identified at a percentage of 53. 9 µg/mL, depending on oil composition. The essential oil tested was Plectranthus (Plectranthus fruticosus - not available commercially), with a sabinyl acetate content of more than 60% (Tisserand and Balacs, 1995). ChemicalBook provide Chemical industry users with SABINYL ACETATE Boiling point Melting point,SABINYL ACETATE Density MSDS Formula Use,If You also need to SABINYL ACETATE Other information,welcome to contact us. 0]hexan-3-ol 3-acetate, Sabinyl acetate Empirical Formula (Hill Notation): C12H18O2 CAS Number: Oct 1, 2025 · Trans -Sabinyl acetate demonstrates strong accumulation in both phases (KEO = 2. (Z)-sabinyl acetate cis-sabinyl acetate Notes: None found Home EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes Search Category: natural substances and extractives US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Visit ChemicalBook To find more SABINYL ACETATE (3536-54-7) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. 1%) and trans-sabinyl acetate (Table 5, ID 14) (11. 3). hmdb. 1 μg/mL (Table 3). Contribution to the study of Salvia lavandulifolia essential oil: potential toxicity attributable to sabinyl acetate Jan 1, 2012 · main compounds for Klaipeda and Druskininkai populations, respectively. GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) Flammable liquids (Category 3), H226 Acute toxicity, Oral (Category 3), H301 Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 For the full text of the H-Statements mentioned in this Section, see Section 16. Use this link for bookmarking this species for future reference. As with any other substance, however, there are some precautions you should observe Sabinyl acetate, a chemical compound used in scientific research, is an intriguing substance with diverse applications. 3%), while other samples with equivalent amounts of Oct 30, 2024 · Learn about the chemical compound Sabinyl acetate, its molar weight, SMILES code, IUPAC, targets (proven or predicted), 2D and 3D structure and so on. Jan 21, 2024 · Chemsrc provides Sabinyl acetate (CAS#:3536-54-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. 3 to 22. Mar 26, 2015 · The effect of trans-sabinol (A), trans-sabinyl acetate (B), trans-sabinyl formate (C), trans-sabinyl tiglate (D) and trans-sabinyl senecioate (E) (in doses of 12. Our Sabinyl acetate is confirmed by NMR. Meanwhile, it should be also mentioned about the toxic effects of other constituents that are present in wormwood EOs, such as artemisia ketone, sabinene, sabinol, sabinyl acetate, 1,8-cienole, etc. 5 mg/kg with some exceptions (35 mg/kg in bitter drinks). Cosperec: Contribution to the Study of Salvia lavandulifolia Essential Oil: Potential Toxicity Attributable to Sabinyl Acetate. Spanish sage (Salvia lavanda4folia Vahi. Found in Nature Materials Catalog information The result indicates that the abortifacient effect of Juniperus sabina essential oil is related to an implantation inhibiting effect, induced by sabinyl acetate, the mechanism of which is being investigated. 0]hex-3-yl acetate (4-methylidene-1-propan-2-yl-3-bicyclo [3. According to a study published in 1964, sabinene, sabinol and sabinyl acetate are highly toxic metabolites (Casares, 1964). absinthium oils were found to be those containing appreciable amount of trans -sabinyl acetate (45. 26 mmol/L), the tested compounds exert influence on both the peripheral and central nervous systems (in the hot plate test, trans-sabinyl tiglate, at 50 mg/kg, produced a 140% baseline increase 15 min after the treatment) and to moderately inhibit acetylcholinesterase (at the concentration Jan 1, 2000 · Birth defects The only essential oil compound that has been shown to have strong terato- genie effects in laboratory animals, is that of sabinyl acetate. Dec 5, 2010 · IUPAC Standard InChIKey: PBWRFXQNNGSAQG-UHFFFAOYSA-N Copy Sheet of paper on top of another sheet CAS Registry Number: 3536-54-7 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file The 3d structure may be viewed using Java or Javascript. Identification Taxonomy Biological Properties Physical Properties Toxicity Profile Spectra Concentrations Links References XML Visit ChemicalBook To find more SABINYL ACETATE (3536-54-7) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. Pregnant dams were injected s. Functional use (s) - natural substances and extractives(E)-sabinyl acetate trans-sabinyl acetate Supplier Sponsors Feb 27, 2021 · Experiments with sabinyl acetate-rich oils suggest substantial reproductive toxicity risks. 2%) and (cis + trans) thujones (12. 0]hexan-3-ol, 4-methylene-1- (1-methylethyl)-, acetate cis-Sabinyl acetate trans-Sabinyl acetate Other names: (E)-Sabinyl acetate; Sabinyl acetate, trans Permanent link for The most toxic A. Production. (15, 45 and 135 mg of this fraction/kg body weight) on days 6 to 15 of gestation. Dec 5, 2010 · trans-Sabinyl acetate Other names: (E)-Sabinyl acetate; Sabinyl acetate, trans Permanent link for this species. Experiments with sabinyl acetate-rich oils suggest substantial reproductive toxicity risks. 03-0. The Essential Oil of Wormwood is extracted by steam distillation of its leaves, twigs, and flowering tops and is chiefly composed of alpha-thujone, beta-thujone, geranyl propionate, linalyl acetate, myrcene, sabinene, trans sabinol, and trans sabinyl acetate. (23) Other sabinyl acetate containing essential oils are Savin (Juniperus sabina, 20% to 53% sabinyl acetate), Juniperus pfitzeriana (not available commercially) and Spanish Sage (Salvia Approval Year Unknown 149124 Name Type Language Bicyclo [3. Use The essential oil tested was Plectranthus (Plectranthus fruticosus - not available commercially), with a sabinyl acetate content of more than 60%. 2 Special hazards arising from the substance Harmful/toxic vapours, carbon oxides may be released during the fire. Pages, I. Feb 27, 2021 · It acts through inhibiting implantation of the embryo [111]. This work summarizes the important studies on the reproductive effects of essential oil constituents anethole, apiole, citral, camphor, thymoquinone, trans-sabinyl acetate, methyl salicylate, thujone, pulegone, β-elemene, β-eudesmol, and costus lactone, among others. Sabinyl acetate，也称为沙比醇醋酸酯，是一种有机化合物。它是粘稠液体，具有蜜橙和松树味道。以下是有关Sabinyl acetate的详细信息： 性质：Sabinyl acetate是无色到浅黄色的液体，具有特殊的香味。它溶于醇和醚类溶剂，但不溶于水。 制法：Sabinyl acetate的合成方法一般是通过将沙比醇（Sabinol）与醋酸 May 25, 2023 · SABINYL ACETATE (CAS 3536-54-7) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices A fraction of the essential oil of Salvia lavandulifolia containing 50% sabinyl acetate was used to evaluate its fetotoxic potential in mice. 2%) and (cis+trans) thujones (12. 0]hexan-3-yl acetate Bicyclo [3. In this study, a variety of choline chloride (ChCl)-based natural deep eutectic solvents (NADES) were used as co-solvents for the hydrodistillation of nutmeg with the aim to obtain M. absinthium essential oils are rich in myrcene, trans -thujone, cis -epoxyocimene, cis -chrysanthenyl acetate, and trans -sabinyl acetate are the most common compounds found in [12, 13]. Order now can get a discount! Toxicity tests of wild wormwood essential oils were performed using the brine shrimp (Artemia sp. 0]hex-3-yl acetate, (1S,3R,5S)-4-Methylene-1- (1-methylethyl)bicyclo [3. Functional use (s) - natural substances and extractivesUS / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Functional use (s) - natural substances and extractives(E)-sabinyl acetate trans-sabinyl acetate Supplier Sponsors The result indicates that the abortifacient effect of Juniperus sabina essential oil is related to an implantation inhibiting effect, induced by sabinyl acetate, the mechanism of which is being investigated. 35) despite a minor reduction in the essential oil (KEO = −0. We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production. 3%), while other samples with equivalent amounts of sabinyl acetate, but without thujones were determined to be notably less toxic. 0]hexan-3-ol, 4-methylene-1- (1-methylethyl)-, 3-acetate, (1S,3R,5S)- Source: Preferred Name English Sabinyl acetate Source: Common Name English Code System Code Type Description CAS Sources: 53833-85-5 Created by admin on Mon Mar 31 19:59:10 GMT 2025 , Edited by admin on Mon Mar 31 19:59:10 GMT 2025 PRIMARY EPA CompTox Source . Thisalsosuggestedthat5 Dec 5, 2010 · IUPAC Standard InChIKey: PBWRFXQNNGSAQG-SAIIYOCFSA-N Copy Chemical structure: This structure is also available as a 2d Mol file Stereoisomers: (1S,3S,5S)-1-Isopropyl-4-methylenebicyclo [3. Fournier, N. BioCrick is a famous high-purity natural products manufacturer. , 1983). 4%), as well as their rare esters. g. Learn about the chemical compound cis-Sabinyl acetate, its molar weight, SMILES code, IUPAC, targets (proven or predicted), 2D and 3D structure and so on. 28% while rest of the components were less than 10%. 174units higher(RI1414and1465,respectively). Rela- tive to the value of RI oftrans-sabinyl acetate (RI 1291), RIs of compounds5and6(DB5-MScolumn)werefor123,i. 7), making it one of the most prominent compounds. Alongside moderate acute toxicity (LD50 (48 h) = 0. 0]hexan-3-ol 3-acetate,Sabinyl acetate at Sigma-Aldrich IUPAC Standard InChIKey: PBWRFXQNNGSAQG-PQDIPPBSSA-N Copy Chemical structure: This structure is also available as a 2d Mol file Stereoisomers: (1S,3S,5S)-1-Isopropyl-4-methylenebicyclo [3. In contrast, cis -thujone rises in the recovery oil from the hydrolate (KHY = 0. 0]hexanyl) acetate (4-methylidene-1-propan-2-yl-3-bicyclo [3. Research. ca naturalproducts. falcata oil trans-sabinyl formate and tiglate have been reported to have moderate acute toxicity and acetylcholinesterase inhibitory activities [48]. It possesses aromatic properties that make it suitable for perfumes and fragrance industry. Information on this page: Gas Chromatography References Notes Gas Chromatography References Notes Options: Switch to calorie-based units Switch to calorie-based units Sabinyl acetate Synonyms: cis-Sabinyl acetate, (1S,3R,5S)-1-Isopropyl-4-methylenebicyclo [3. Since there is no established no observed adverse effect level (NOAEL), it is best to completely avoid sabinyl acetate-rich essential oils and any preparations containing them in pregnancy, especially during the first trimester. Jun 1, 2015 · According to Casares (1964), sabinene, sabinol and sabinyl acetate are the metabolites responsible for the toxicity of Juniperus sabina, which is included in the FDA (US Food and Drug administration) Poisonous Plant Database. 5 (- -), 25 Apr 10, 2023 · The most toxic A. Who Should Avoid Sabinyl acetate phyproof® Reference Substance; CAS Number: 53833-85-5; Synonyms: cis-Sabinyl acetate, (1S,3R,5S)-1-Isopropyl-4-methylenebicyclo [3. c. uif qnc2 wc 4wog6h dcl pjmr5 xsm jqfnr 0yei ho7b